The Swiss 3R Network existed from 2013 until 2019. The Federal Food Safety and Veterinary Office (FSVO) initiated and financially supported the Swiss3RNetwork, to promote exchange of 3R-relevant information among researchers in Switzerland. Prof. Dr Thorsten Buch from the University of Zurich moderated the online platform, which successfully compiled a wealth of 3R-relevant expertise that is widely scattered in various teams and laboratories within the country. Thanks to the platform, researchers were able to disseminate the accumulated knowledge, knowhow and expertise in the area of the 3R principles. From 2019, the network's activities are integrated into the Swiss 3RCC.