2020 Call: Refining intracerebral administration of drugs with sonoporation-activated microbubbles
Project OC-2020-015
Intracerebral administration of central nervous system (CNS) active agents through intracranial surgery is a widely used…
2020 Call: Identifying new regulators of cell invasion in colorectal cancer using the Drosophila adult intestine
Project OC-2020-011
Colorectal cancer (CRC) is a cancer of the colon and the rectum. It is the third most prevalent cancer worldwide and is the…
2020 Call: Best practice guidance for including sex as a biological variable in animal research
Project OC-2020-004
In animal research, a strong bias towards using male animals is apparent in most disciplines. By using animals of only one sex,…
2020 Call: Reducing the need for lethal health monitoring in trout
Project OC-2020-003
Proliferative Kidney Disease (PKD) is a deadly parasitic fish disease that is classified as reportable and that has to be…
2020 Call: Experimental toolkit to evaluate cell-based therapies in the mouse brain
Project OC-2020-002
For every 100 prospective therapies in clinical development, approximately 90 are never approved for clinical use. This…
2019 Call: Engineering a novel cell-based model for assessing materno-fetal drug transfer during pregnancy
Project OC-2019-019
The human placenta is a vital organ that acts as a barrier between the circulation of the mother and the growing fetus. It…
2019 Call: Development of a platform for GU cancer patient-derived organoids
Project OC-2019-003
Understanding and overcoming cancer therapy resistance is a major overarching goal of our precision oncology program at the…
2019 Call: IPF-on-Chip: Replacing the bleomycin induced lung injury and fibrosis model with lung-on-chip technology
Project OC-2019-025
Today, new antifibrotic drugs for idiopathic pulmonary fibrosis (IPF) are tested in mice with the bleomycin-induced lung-injury…
2019 Call: BEHAVE: A toolkit for deep-behavior profiling of laboratory rodents
Project OC-2019-009
Many hundred-thousand rodents, mostly mice, are used in behavioural neuroscience research every year. This is necessary, because…
2018 Call: Nutritional requirements of fish cell lines – development of a serum-free culture medium (L-15Plus)
Project OC-2018-001
Manmade chemicals have become an essential commodity in our daily lives, from personal care to medicine and agriculture.…