During the current finance period (2021-2024), the 3RCC will launch several targeted calls to promote knowledge transfer, open 3Rs science, young researchers and progress within the field of refinement. Through Knowledge Transfer Grants younger researchers may apply for funding of a short-term stay with another national or international research group to learn a novel 3Rs approach and implement it at their home institution. Scientists may also apply for Open 3Rs Science Grants, which can be used to support preregistration, open access publications, open-source software tools or other resources, which help make research as transparent and accessible as possible. The centre is also offering Refinement Grants of up to CHF 20,000 to promote training and dissemination of already existing refinement approaches and to encourage development of further refinement approaches. With its 3Rs Doctorate Programme the centre wants to encourage a new generation of researchers to put new methods into active practice and disseminate them, thereby advancing the application of the 3Rs principle.